The Agilent one hundred automatic disintegration apparatus is a fully programmable Answer that provides trusted disintegration testing results. Our disintegration testing programs are compact and simple to deal with, featuring precise temperature Handle and Assembly regulatory compliance needs.
Follow individual characteristics necessary for the powerful and successful carry out of the administration program audit.
Observe the number of cycle /oscillation in one minute. Repeat the test following the interval for 5 min. and history the volume of cycle /Oscillation According to the calibration format, repeat the exact same procedure for remaining aspect jar and file the observation in calibration format.
Total disintegration: That state in which any residue of your unit, apart from fragments of insoluble coating or capsule shell, remaining over the monitor on the test apparatus or adhering on the lessen surface area in the disk, if employed, is a delicate mass obtaining no palpably business Main.
The test evaluates how immediately these dosage sorts stop working into smaller particles or disintegrate when exposed to a specific medium, normally drinking check here water or simulated gastric fluid.
Intuitive touchscreen Regulate with icon-based menu construction simplifies operation and Plainly shows test parameters all over run
Be aware : Just about every instrument is calibrated with the respective serial variety bathtub. Never interchange the bath.
The disintegration test is An important high quality control test executed from the pharmaceutical market to make sure that the dosage types will disintegrate and launch their active elements properly in get more info your body.
Improve routine maintenance cycles and asset lifetime via a superior knowledge of asset situation, comparing PD outcomes after some time to detect trends
Suspend the assembly in the beaker made up of the desired liquid and function the apparatus for the required time. Clear away the assembly through the liquid. The disintegrating tablets or capsules move the test if all of these have disintegrated.
If a Show on temperature display displays a ‘P.O’, this means the probe is open up. Join the probe. Also, a Display screen of ‘P S’ shows that the probe is a short condition.
For changing the common basket to special coated Edition for testing hard or tender gelatine capsules accepting to USP Chapter
Document the reading through in calibration format following interval as per calibration structure, repeat exactly the same method for remaining side jar and record the observation in calibration structure.
Disintegration is always to be Executed to determine whether or not tablets or capsules disintegrate in the prescribed time when placed in the liquid medium at the experimental ailments.